Extracellular Vesicles Scar Rejuvenation

Trusted Experts in Scar Restoration in Charlotte, NC

Extracellular Vesicles are nanovesicles derived from mesenchymal stems cells (MSCs).

Extracellular Vesicles are nanovesicles derived from mesenchymal stems cells (MSCs). They work by generating signals that allow cells within the body to communicate with each other and ultimately direct the body's response to inflammation, injury, and healing. MSC-derived extracellular vesicles contain a multitude of growth factors and regulatory molecules that allow for significant tissue repair and regenerative wellness. They do not contain cellular DNA, cannot replicate, have no metabolic activity, and are extensively tested to provide the highest safety profile and purity standards.

Approximately 100 million people suffer annually with scarring pain and discomfort

1. Scarring is associated with depression, social avoidance and disfigurement, and may have devastating consequences for patients, including limitation of movement, poor aesthetic appearance, permanent disability and other effects

2. Mitigating scar formation is highly desirable for patients. Scar formation is the result of a complex process involving inflammatory, proliferative (the development of granulation tissue) and remodeling phases.

In the study provided in the link below, the researchers did see an overall reduction in the quality of scars and the different molecules produced during the formation of scars in general. Exosome therapy can reduce the appearance of scars and helps restore the skin to normal.


2. Yates CC, Hebda P, Wells A. Skin wound healing and scarring: fetal wounds and regenerative restitution. Birth defects research. Part C, Embryo today: reviews. 2012;96:325–333. doi: 10.1002/bdrc.21024. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
3. Martin P. Wound healing–aiming for perfect skin regeneration. Science. 1997;276:75–81. doi: 10.1126/science.276.5309.75. [PubMed] [CrossRef] [Google Scholar]
4. Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound repair and regeneration. Nature. 2008;453:314–321. doi: 10.1038/nature07039. [PubMed] [CrossRef] [Google Scholar]
5. Broughton G, 2nd, Janis JE, Attinger CE. The basic science of wound healing. Plastic and reconstructive surgery. 2006;117:12S–34S. doi: 10.1097/01.prs.0000225430.42531.c2. [PubMed] [CrossRef] [Google Scholar]